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Kassu is a public health professional with more than two decades of experience in clinical medicine, academia, research, program management, and policy development and analysis across the public sector and the United Nations in the areas of capacity building, primary health care, health systems development and strengthening, policy development and analysis, communicable and non-communicable diseases prevention and control, and child health.  

Currently, he is health systems officer at the World Health Organization Country Office for Ethiopia. In this capacity, he supports the use of evidence in health policy development and health systems strengthening. 

He has also adjunct academic positions at Jimma University and Addis Continental Institute of Public Health. 

He has a Doctor of Medicine (MD) from Gondar College of Medical Sciences, an MPH from the University of Gondar, and a Ph.D. in the Politics of Health Policy from McMaster University in Canada. He also completed his residency in Pediatrics and Child Health at Addis Ababa University.